Medical
In Vivo
Non-Melanoma Skin Cancer Research
Squamous Cell Carcinoma and Actinic Keratosis


1
Digital follow-up by means of dermatoscopy and reflectance confocal microscopy of actinic keratosis treated with Imiquimod 3.75% cream.

Benati E, Longhitano S, Pampena R, Mirra M, Raucci M, Pellacani G, Longo C. J Eur Acad Dermatol Venereol. 2019 Dec 14. doi: 10.1111/jdv.16143.

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2
The actinic dysplasia syndrome - diagnostic approaches defining a new concept in field carcinogenesis with multiple cSCC

Dejonckheere G, Suppa M, Del Marmol V, Meyer T, Stockfleth E. J Eur Acad Dermatol Venereol. 2019 Dec;33 Suppl 8:16-20. doi: 10.1111/jdv.15949.

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3
The role of reflectance confocal microscopy in the diagnosis and management of squamous cell carcinoma in situ treated with photodynamic therapy.

Teoh YL, Kuan LY, Chong WS, Chia HY, Thng TGS, Chuah SY. Int J Dermatol. 2019 Jul 8. doi: 10.1111/ijd.14581.

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4
Effects of topical piroxicam and sun filters in actinic keratosis evolution and field cancerization: a two-center, assessor-blinded, clinical, confocal microscopy and dermoscopy evaluation trial.

Agozzino M, Russo T, Franceschini C, Mazzilli S, Garofalo V, Campione E, Bianchi L, Milani M, Argenziano G. Curr Med Res Opin. 2019 Jun 13:1-8. doi: 10.1080/03007995.2019.1626227.

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6
Non-invasive imaging techniques for early diagnosis of radiation-induced squamous cell carcinoma of the lip.

Lupu M, Căruntu A, Moraru L, Voiculescu VM, Boda D, Tănase C, Căruntu C.

Rom J Morphol Embryol. 2018;59(3):949-953.

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7
Management of clinical and subclinical actinic keratoses with histological and immunohistochemical assessments by confocal microscopy.

Mazzella C, Greco V, Costa C, Scalvenzi M, Russo D, Savastano R, Staibano S, Fabbrocini G.

Dermatol Ther. 2018 Sep;31(5):e12672. doi: 10.1111/dth.12672.

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8
Sequential treatment of actinic keratosis with cryotherapy and ingenol mebutate: reflectance confocal microscopy monitoring of efficacy and local skin reaction.

Pasquali P, Segurado-Miravalles G, González S.

Int J Dermatol. 2018 Oct;57(10):1178-1181. doi: 10.1111/ijd.14164.

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9
Reflectance confocal microscopy: a crucial role for actinic keratosis treatment monitoring.

Pellacani G, Longo C.; J Eur Acad Dermatol Venereol. 2018 Jul;32(7):1055. doi: 10.1111/jdv.15091.

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10
Assessment of the Effect of 3% Diclofenac Sodium on Photodamaged Skin by Means of Reflectance Confocal Microscopy.

Segurado-Miravalles G, Jiménez-Gómez N, Muñoz Moreno-Arrones O, Alarcón-Salazar I, Alegre-Sánchez A, Saceda-Corallo D, Jaén-Olasolo P, González-Rodríguez S.;

Send to

Acta Derm Venereol. 2018 Jun 1. doi: 10.2340/00015555-2984.

 

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11
Dermoscopy and reflectance confocal microscopy for monitoring the treatment of actinic cheilitis with ingenol mebutate gel: Report of three cases.

Benati E, Pampena R, Bombonato C, Borsari S, Lombardi M, Longo C.

Dermatol Ther. 2018 Apr 24:e12613. doi: 10.1111/dth.12613.

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12
Non-invasive imaging of actinic cheilitis and squamous cell carcinoma of the lip.

Lupu M, Caruntu A, Caruntu C, Boda D, Moraru L, Voiculescu V, Bastian A.

Mol Clin Oncol. 2018 May;8(5):640-646. doi: 10.3892/mco.2018.1599.

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13
The role of reflectance confocal microscopy in a case of Bowen's disease difficult to diagnose.

Karaarslan I, Tepret S, Yildiz S, Yaman B, Ozdemir F.

Dermatol Pract Concept. 2018 Jan 31;8(1):63-65. doi: 10.5826/dpc.0801a15.

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14
In vivo Confocal Laser Microscopy for monitoring of actinic keratosis treatment: a comparison with histopathologic assessment after treatment with topical 5% 5-fluorouracil.

Ishioka P, Maia M, Rodrigues SB, Facchini-Lellis R, Hirata SH. J Eur Acad Dermatol Venereol. 2017 Nov 24. doi: 10.1111/jdv.14716

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15
Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma.

Hocker S, Rabinovitz HS, Oliviero M, Grant-Kels J, Scope A. Dermatol Pract Concept. 2017 Oct 31;7(4):39-42. doi: 10.5826/dpc.0704a09.

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17
Reflectance Confocal Microscopy Criteria of Pigmented Squamous Cell Carcinoma In Situ.

Shahriari N, Grant-Kels JM, Rabinovitz HS, Oliviero M, Scope A. Am J Dermatopathol. 2017 Aug 9. doi: 10.1097/DAD.0000000000000938.

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18
Dermoscopic and reflectance confocal microscopy features of cutaneous squamous cell carcinoma.

Manfredini M, Longo C, Ferrari B, Piana S, Benati E, Casari A, Pellacani G, Moscarella E. J Eur Acad Dermatol Venereol. 2017 Jul 11. doi: 10.1111/jdv.14463.

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19
Reflectance confocal microscopy of vulvar epithelial neoplasia: a pilot study.

Fouques C, Dorez M, Le Duff F, Cardot-Leccia N, Chevallier A, Lacour JP, Bahadoran P, Bongain A. Br J Dermatol. 2017 Apr 12. doi: 10.1111/bjd.15573.

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20
From actinic keratosis to squamous cell carcinoma: pathophysiology revisited.

Fernandez Figueras MT. J Eur Acad Dermatol Venereol. 2017 Mar;31 Suppl 2:5-7. doi: 10.1111/jdv.14151.

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21
The current role of in vivo reflectance confocal microscopy within the continuum of actinic keratosis and squamous cell carcinoma: a systematic review.

Nguyen KP, Peppelman M, Hoogedoorn L, Van Erp PE, Gerritsen MP. Eur J Dermatol. 2016 Dec 1;26(6):549-565. doi: 10.1684/ejd.2016.2872.

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24
Biological Effects of Ingenol Mebutate Gel in Moderate to Severe Actinic Fields Assessed by Reflectance Confocal Microscopy: A Phase I Study.

Ulrich M, Lange-Asschenfeldt S, Skak K, Skov T, Østerdal ML, Röwert-Huber HJ, Zibert JR, Stockfleth E. J Drugs Dermatol. 2016 Oct 1;15(10):1181-1189.

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26
Histological examination confirms clinical clearance of AKs following treatment with ingenol mebutate 0.05% gel.

Ulrich M, Reinhold U, Skov T, Søndergaard RE, Guitera P. Br J Dermatol. 2016 Aug 12. doi: 10.1111/bjd.14968.

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27
In vivo reflectance confocal microscopy features of a large cell acanthoma: report of a case.

Neda Shahriari, Jane M. Grant-Kels, Harold S. Rabinovitz, Margaret Oliviero, and Alon Scope. Dermatol Pract Concept. 2016 Jul 31;6(3):67-70. doi: 10.5826/dpc.0603a14.

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28
A pink papule on the back of an 82-year-old man: an example of the buttonhole sign on reflectance confocal microscopy.

Que SK, Fraga-Braghiroli N, Grant-Kels JM, Rabinovitz HS, Oliviero M, Scope A. Dermatol Pract Concept. 2016 Jul 31;6(3):1-2. doi: 10.5826/dpc.0603a01.

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29
Histopathology and reflectance confocal microscopy features of photodamaged skin and actinic keratosis.

Tan JM, Lambie D, Sinnya S, Sahebian A, Soyer HP, Prow TW, Ardigò M. J Eur Acad Dermatol Venereol. 2016 Jun 14. doi: 10.1111/jdv.13699.

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30
Dermoscopic and Reflectance Confocal Microscopy Findings in Extra-genital HPV16-associated Pigmented Squamous Cell Carcinoma in situ.

Blumetti TP, Scope A, Macedo MP, Ferreira JB, Gomes EE, Enokihara MY, Pinto CA, Nascimento MM, Rezze GG, Braga JC. Acta Derm Venereol. 2016 Mar 15. doi: 10.2340/00015555-2399.

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31
In-vivo confocal microscopy efficacy assessment of daylight photo dynamic therapy in actinic keratosis patients.

Br J Dermatol. 2016 Mar 7. doi: Jafari SM, Timchik T, Hunger RE. 10.1111/bjd.14517.

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32
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33
Non-invasive diagnostic techniques in the diagnosis of squamous cell carcinoma.

Warszawik-Hendzel O, Olszewska M, Maj M, Rakowska A, Czuwara J, Rudnicka L, J Dermatol Case Rep. 2015 Dec 31;9(4):89-97. doi: 10.3315/jdcr.2015.1221.

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34
Treatment monitoring of 0.5% 5-fluorouracil and 10% salicylic acid in clinical and subclinical actinic keratoses with the combination of optical coherence tomography and reflectance confocal microscopy.

Malvehy J, Alarcon I, Montoya J, Rodríguez-Azeredo R, Puig S, J Eur Acad Dermatol Venereol. 2016 Feb;30(2):258-65. doi: 10.1111/jdv.13445.

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35
Grading keratinocyte atypia in actinic keratosis: a correlation of reflectance confocal microscopy and histopathology.

Pellacani G, Ulrich M, Casari A, Prow TW, Cannillo F, Benati E, Losi A, Cesinaro AM, Longo C, Argenziano G, Soyer HP., J Eur Acad Dermatol Venereol. 2015 Nov;29(11):2216-21. doi: 10.1111/jdv.13215.

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36
Evaluation of the therapeutic results of actinic keratosis treated with topical 5% fluorouracil by reflectance confocal laser microscopy: preliminary study.

Ishioka P, Maia M, Rodrigues SB, Marta AC, Hirata SH., An Bras Dermatol. 2015 May-Jun;90(3):426-9. doi: 10.1590/abd1806-4841.20153437.

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37
A new vision of actinic keratosis beyond visible clinical lesions.

Malvehy J., J Eur Acad Dermatol Venereol. 2015 Jan;29 Suppl 1:3-8. doi: 10.1111/jdv.12833.

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38
Reflectance confocal microscopy: hallmarks of keratinocyte cancer and its precursors.

Prow TW, Tan JM, Pellacani G., Curr Probl Dermatol. 2015;46:85-94. doi: 10.1159/000366541.

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39
Reflectance confocal microscopy: non-invasive distinction between actinic keratosis and squamous cell carcinoma.

Peppelman M, Nguyen KP, Hoogedoorn L, van Erp PE, Gerritsen MJ., J Eur Acad Dermatol Venereol. 2014 Oct 30. doi: 10.1111/jdv.12806.

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41
Field Cancerisation Improvement with Topical Application of a Film-Forming Medical Device Containing Photolyase and UV Filters in Patients with Actinic Keratosis, a Pilot Study

Puig S, Puig-Butillé JA, Díaz MA, Trullas C, Malvehy J, J Clin Exp Dermatol Res 5: 220.

doi:10.4172/2155-9554.1000220

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42
Monitoring Treatment of Field Cancerisation with 3% Diclofenac Sodium 2.5% Hyaluronic Acid by Reflectance Confocal Microscopy: A Histologic Correlation.

Malvehy J, Roldán-Marín R, Iglesias-García P, Díaz A, Puig S.; Acta Derm Venereol. 2014 Apr 3. doi: 10.2340/00015555-1860.

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43
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44
Morphologic grading and treatment of facial actinic keratosis.

Zalaudek I, Piana S, Moscarella E, Longo C, Zendri E, Castagnetti F, Pellacani G, Lallas A, Argenziano G., Clin Dermatol. 2014 Jan-Feb;32(1):80-7. doi: 10.1016/j.clindermatol.2013.05.028.

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45
Pigmented squamous cell carcinoma of the nail bed presenting as a melanonychia striata: diagnosis by perioperative reflectance confocal microscopy.

Fernandes Massa A, Debarbieux S, Depaepe L, Dalle S, Balme B, Thomas L.; Br J Dermatol. 2013 Jul;169(1):198-9. doi: 10.1111/bjd.12243.

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46
In vivo Reflectance Confocal Microscopy: A Useful Tool to Select the Location of a Punch Biopsy in a Large, Clinically Indistinctive Lesion.

Peppelman M, Wolberink EA, Koopman RJ, van Erp PE, Gerritsen MJ.; Case Rep Dermatol. 2013 Apr 25;5(1):129-32. doi: 10.1159/000351258.

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47
The vasculature of nonmelanocytic skin tumors on reflectance confocal microscopy: vascular features of squamous cell carcinoma in situ.

Ahlgrimm-Siess V, Cao T, Oliviero M, Hofmann-Wellenhof R, Rabinovitz HS, Scope A.; Arch Dermatol. 2011 Feb;147(2):264.

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48
Follow-up of actinic keratoses after shave biopsy by in-vivo reflectance confocal microscopy--a pilot study.

Richtig E, Ahlgrimm-Siess V, Koller S, Gerger A, Horn M, Smolle J, Hofmann-Wellenhof R.; J Eur Acad Dermatol Venereol. 2010 Mar;24(3):293-8, JEADV. JDV3410. DOI: 10.1111|j. 1468-3083.2009.03410.x.2009:216-29, 2009

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49
Non-invasive diagnosis and monitoring of actinic cheilitis with reflectance confocal microscopy

Ulrich M, González S, Lange-Asschenfeldt B, Roewert-Huber J, Sterry W, Stockfleth E, Astner S., JEADV. 2010. DOI: 10.1111/j.1468-3083.2010.03777.x

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50
Reflectance confocal microscopy for noninvasive monitoring of therapy and detection of subclinical actinic keratoses.

Ulrich M, Krueger-Corcoran D, Roewert-Huber J, Sterry W, Stockfleth E, Astner S.; Dermatology. 2010;220(1):15-24 DOI: 10.1159/000254893. 2009

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51
Reflectance confocal microscopy criteria for squamous cell carcinomas and actinic keratoses.

Rishpon A, Kim N, Scope A, Porges L, Oliviero MC, Braun RP, Marghoob AA, Fox CA, Rabinovitz HS.; Arch Dermatol. 2009 Jul;145(7):766-72.

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52
Discrimination of Actinic Keratoses from Normal Skin with Reflectance Mode Confocal Microscopy

Horn M, Gerger A, Ahlgrimm-Siess, V, Weger W,

Koller S, Kerl H, Samonigg H, Smolle J, Hoffman-

Wellenhof R.; Dermatol Surg 2008; 34:620–625.

DOI 10.1111/j.1524-4725.2007.34117.x

 

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53
Clinical Applicability of in vivo Reflectance Confocal Microscopy for the Diagnosis of Actinic Keratoses

Ulrich M, Maltusch A, Ruis-Dias F, Rowert-Huber J, González S, Sterry W, Stockfleth E,

Astner S.; Dermatol Surg 2008;34:610–619.

DOI 10.1111/j.1524-4725.2008.34195.x

 

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54
Differentiation between Actinic Keratoses and Disseminated Superficial Porokeratoses with Reflectance Confocal Microscopy

Ulrich M, Forschner T, Rowert-Huber J, Gonzalez S, Stockfleth E.; Br J Dermatol. May 2007;156

Suppl 3:47-52. DOI 10.1111/j.1365-2133.2007.07862.x

 

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55
Actinic keratosis: non-invasive diagnosis for field cancerisation

Ulrich M, Maltusch A, Rowert-Huber J, Gonzalez S, Sterry W, Stockfleth E, Astner S.; British Journal of

Dermatology. 2007; 156 (Suppl. 3), 13-17.

DOI 10.1111/j.1365-2133.2007.07865.x

 

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56
5% Imiquimod Cream and Reflectance-Mode Confocal Microscopy as Adjunct Modalities to Mohs Micrographic Surgery for Treatment of Basal Cell Carcinoma

Torres A, Niemeyer A, Berkes B, Marra D,

Schanbacher C, González S, Owens M, Morgan B.; Dermatol Surg. Dec 2004; 30(12 Pt 1):1462-9.

DOI 10.1111/j.1524-4725.2004.30504.x

 

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58
Confocal Laser Microscopic Imaging of Actinic Keratosis In Vivo: A Preliminary Report

Aghassi D, Anderson RR, González S.; J Am Acad Dermatol. July 2000; 43(1 Pt 1):42-8. DOI 10.1067/mjd.2000.105565

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