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Clonal seborrheic keratosis: dermoscopic and confocal microscopy characterization.

Longo C, Zalaudek I, Moscarella E, Lallas A, Piana S, Pellacani G, Argenziano G., J Eur Acad Dermatol Venereol. 2014 Oct;28(10):1397-400. doi: 10.1111/jdv.12261.

ABSTRACT

BACKGROUND: The diagnosis of clonal seborrheic keratosis may be challenging clinically and histologically.

 

OBJECTIVE: In our study, we describe the common aspects of this benign entity that show peculiar dermoscopic and confocal findings.

 

METHODS: A total of nine clonal seborrheic keratosis were analyzed.

 

RESULTS: Upon dermoscopy, it reveals the presence of globular-like structures and sharply demarcated borders whereas confocal microscopy displays the typical intraepidermal nesting of pigmented keratinocytes that permits to have a reliable in vivo diagnosis.

 

CONCLUSIONS: Dermoscopy and confocal microscopy permit to in vivo diagnose this variant of seborrheic keratosis.

 

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